Create Post
Understanding vaccine response can affect antibody responses
New findings from a meta-analysis published in 'Nature Immunology' examine the biological mechanisms role in determining varied responses to vaccinations among people, which could have global implications for the development and administration of vaccines. As part of a series of studies for The Human Immunology Project Consortium (HIPC), a network of national research institutions studying the range of responses to different infections and vaccinations, Emory researchers analyzed the molecular characteristics of 820 healthy young adults who were immunized with 13 different vaccines to identify specific biomarkers that generate antibody response to vaccines. Slim Fourati, PhD, bioinformatic research associate at Emory University and first author on the paper said, ."We were surprised because inflammation is usually depicted as something that is bad, tese data indicate that some types of inflammation can actually foster a stronger response from a vaccine." More research is needed to determine the cause of this inflammation in otherwise healthy adults" says Fourati. Better understanding of how various pre-vaccine immune states impact antibody responses opens the possibility of altering these states in more vulnerable individuals. This work will help enable improved, more efficient clinical trials for the development of new vaccines. Source - Zee News
- 3
- 0
- ₹0
